Publications
Independent career
M.-C. Materis, W. A. L. van Otterlo, D. Berthold, Concise Access to Naphthalene Building Blocks for Naphthylisoquinoline Alkaloid Synthesis via Transition-Metal Catalysis ChemCatChem 2024, e202401070. DOI: 10.1002/CCTC.202401070.
D. Groß, W. van Otterlo, O. Trapp, D. Berthold, Atroposelective Ni(II)-Catalyzed Cross-Coupling Reactions Enable a Deeper Understanding of Negishi Couplings: Isolation and Application of Solid Aryl Higher-Order Zincates Chem. Eur. J. 2023, e202302841. DOI: 10.1002/chem.202302841.
Post-Doc
M. T. Daiger, S. Giofré, D. Berthold, B. Breit, Rhodium-Catalyzed Enantioselective Intramolecular Hydroalkoxylation of Allenes and Application in the Total Synthesis of (R,R,R)-alpha-Tocopherol Chem. Eur. J. 2024, 30, e20242010. DOI: 10.1002/chem.202402010.
S. B. Wagh, D. Berthold, Majeed, L. K. Lewis, D. Schilter, B. Mertens, A. Evidente, W. A. L. van Otterlo, V. Mathieu, A. Kornienko, Sphaeropsidin A C15–C16 Cross-Metathesis Analogues with Potent Anticancer Activity ChemMedChem 2024, 19, e202400288. DOI: 10.1002/cmdc.202400288.
D. Berthold, W. van Otterlo, Unprecedented direct asymmetric total syntheses of 5,8’-naphthylisoquinoline alkaloids from their fully substituted precursors employing a novel Nickel/N,N-ligand-catalyzed atroposelective cross-coupling Chem. Eur. J. 2023, e202302070. DOI: 10.1002/chem.202302070.
A. Haydl, A. Geissler, D. Berthold, Comprehensive Organometallic Chemistry IV. Eds. G. Parkin, K. Meyer, D. O’hare. Amsterdam: Elsevier, 2022, chapter 12.08: Metal-Catalyzed Amination: C–N Bond Formation. DOI: 10.1016/B978-0-12-820206-7.00119-0
D. Berthold, A. M. Haydl, J. C. Leung, U. Scholz, Q. Xiao, Z. Zhu, Synthesis of arylamines in the light of their application in the chemical and pharmaceutical industry. Methodologies in Amine Synthesis. Eds. A. Ricci and L. Bernardi. Weinheim: Wiley-VCH, 2021, chapter 10. DOI: 10.1002/9783527826186.ch10
Undergraduate
D. Berthold, B. Breit, Synthesis of (–)-(R)-Sitagliptin by Rh(I)-catalyzed Asymmetric Hydroamination Eur. J. Org. Chem. 2021, 46, 6247-6249. – In Memory of Klaus Hafner. DOI: 10.1002/ejoc.202100832.
D. Berthold, B. Breit, Total Syntheses of Cylindrocyclophanes Exemplifying the Power of Transition-Metal Catalysis in Natural-Product Synthesis Synlett 2020, The Power of Transition Metals: An Unending Well-Spring of New Reactivity, A-K. DOI: 10.1055/s-0040-1707144.
D. Berthold, B. Breit, Asymmetric Total Syntheses of (–)-Angustureine and (+)-Cuspareine via Rhodium-Catalyzed Hydroamination Org. Lett. 2019, 22, 565-568. DOI: 10.1021/acs.orglett.9b04334.
D. Berthold, J. Klett, B. Breit, Rhodium-Catalyzed Asymmetric Intramolecular Hydroarylation of Allenes: Access to Functionalized Benzocycles Chem. Sci. 2019, 10, 10048-10052. DOI: 10.1039/C9SC03894A.
D. Berthold, A. G. A. Geissler, S. Giofré, B. Breit, Rhodium-catalyzed Asymmetric Intramolecular Hydroamination of Allenes Angew. Chem. Int. Ed. 2019, 58, 9994-9997. DOI: 10.1002/anie.201904833.
D. Berthold, B. Breit, Total Synthesis of (–)-Cylindrocyclophane F: A Yardstick for Probing New Catalytic C–C Bond-Forming Methodologies Chem. Eur. J. 2018, 24, 16770-16773. DOI: 10.1002/chem.201804585.
D. Berthold, B. Breit, Chemo-, Regio- and Enantioselective Rhodium-Catalyzed Allylation of Triazoles with Internal Alkynes and Terminal Allenes Org. Lett. 2018, 20, 598-601. DOI: 10.1021/acs.orglett.7b03708.
A. M. Haydl, D. Berthold, P. A. Spreider, B. Breit, Stereodivergent and Protecting-Group-Free Synthesis of the Helicascolide Family: A Rhodium-Catalyzed Atom-Economical Lactonization Strategy Angew. Chem. Int. Ed. 2016, 55, 5765-5769. DOI: 10.1002/anie.201600632.